Low Libido
The low sex desire is called when the desire for sex is lower than average. This decreased libido leads to un-satisfaction in opposite partner. Even the person who suffers with less i.e. diminished sexual desire & low frequency of sex suffers with various psychological depression disorders. Even the relation between the couples deteriorates. 
Causes of Low libido i.e. diminished sex desire are: - 
Hormones Disorder:
(a) Hypogonadotropic hypogonadism (hypothalamic or pituitary deficiencies)
Hypogonadisms, Hypothyroidisms, Testosterone deficiency, hyperprolactinemias, 
Hypogonadotropics states: Hypothalamic - pituitary deficiencies: Idiopathic GnRH deficiency, Kallman syndromes, Prader-Willi syndromes, Laurence-Moon-Biedl syndromes, pituitary hypoplasia, Trauma, post surgical, postiradiation, Tumour (Adenoma, craniopharyngioma, other), Vascular (pituitary infraction, carotid aneurysm), Infiltrative (Sarcoidosis, histiocytosis, hemochromatosis)
Autoimmune hypophysitis, drug-induced hyperprolactinemia, untreated endocrinopathies, Diabetics Glucorticoid excess, Hypopituitarisms, Cushings disease, Addisons disease. 
Isolated gonadotropin deficiency (non acquired): Pituitary, Hypothalamic 
Associated with multiple pituitary hormone deficiencies: Idiopathic pan hypo pituitarism (hypothalamic defects), Pituitary dysgenesis, Following inflammation, Infiltrative or destructive processes (autoimmune, hemosiderosis),
Fertile eunuch syndrome, Idiopathic hypopituitarism, 
(b) hypogonadism: testicular failure, development defect, drugs, trauma, congenital defect, congenital adrenal hyperplasia, Chromosomal defect, testosterone hormone biosynthetic defect, Mumps orchitis leading to testicular atrophy, Primary testicular defect-disorders of testicular differentiation or inborn errors of testosterone synthesis, Klinefelter syndrome, Other X polysomies (i.e. XXXXY, XXXY)
Rainbow syndrome
(d) Hypothyroidisms
(e) Untreated endocrinopathies & Diabetics
(f) Glucorticoids excess, Cushings disease, Addisons disease
2) Excess asthenia i.e. chronic asthenia is a also a significant cause of low sex desire.
3) Sickle cell disease, chronic cardiac disease, chronic renal disorder, chronic pulmonary dysfunction, chronic hepatic disease, Infections mono-nucleosis, hepatitis, chronic balanitis, chronic prostatitis, and chronic urethritis.
4) Addiction as chronic alcoholism, chronic smoker, heroin or cannabis use.
5) Drugs: Sedative: Narcotics, tranquillizers, amphetamine, cocaine, many antidepressant, and anti-psychotics, anti -hypertensives, many other drugs.
6) Psychiatric disorder as depression, neurosis, & many other psychiatric disorders.
6) Disorders of sex centre: In the brain there is a particular center in the hippocampus part of fore brain, which regulates the desire of sex. Sex center has some well-defined portion, which control different component of normal sexuality. These are as follows as one part of sex center controls sexual desire other parts controls erection, time taken in orgasm enjoy of sexual act including enjoyment of orgasm. So any disorder of sex center due to various causes can lead to less desire. This occurs due to desire controlling portions of sex center does not work properly so that inspite of \not having any physical or mental disorders the patient desire for sex is low. Beside low sex desire patient may be sexually otherwise for or patient may be suffering with impotence, premature ejaculation.
The causes of sex centre dysfunction can be divided into two groups:
Immediate cause
Remote causes. Such a classification is helpful in the treatment of decreased libido. If the loss of desire is due to immediate causes, a removal of these factors results in adequate sexual desire.
If it is due to remote causes, then detailed sex therapy may be necessary for a more lasting cure.
It can cause less sexual desire alone or patient may have associated erectile disorder, premature ejaculation, or lack of enjoyment of sex.
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